TUMOR-COLONIZING E. COLI EXPRESSING BOTH COLLAGENASE AND HYALURONIDASE ENHANCES THERAPEUTIC EFFICACY OF GEMCITABINE IN PANCREATIC CANCER MODELS

Tumor-Colonizing E. coli Expressing Both Collagenase and Hyaluronidase Enhances Therapeutic Efficacy of Gemcitabine in Pancreatic Cancer Models

Desmoplasia is a hallmark feature of pancreatic ductal adenocarcinoma (PDAC) that contributes significantly to treatment resistance.Approaches Sports Bar to enhance drug delivery into fibrotic PDAC tumors continue to be an important unmet need.In this study, we have engineered a tumor-colonizing E.coli-based agent that expresses both collagenase an

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"The commune, site community action and transformation"

Whereas Review argues that current environmental knowing, which requires rethinking actions, evaluate new contexts that affect the needs and motivations of people to participate in the change, we have to reconstruct the environment with "new knowledge environmental "to identify the main negative impacts on the environment, the human environment, ec

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